Biological factors

Most of the evidence that biological factors play a role in the development of neurotic disorders derives from studies in younger subjects (see ChapteL4Z..1, C..h§p.t.e.L 4.7.2 and Chapter.4.7.3). These studies indicate that genetic factors contribute significantly to premorbid vulnerability, but the role that they play in old age is not known. Neuroimaging studies of elderly depressed patients provide only limited information about neurotic disorders, suggesting that patients with milder forms of depression and higher anxiety scores are more likely than severely depressed patients to have normal CT scans. It has been suggested that some anxiety disorders following stroke may be related to lesion location.(8)

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