Antiandrogens

Ciproterone acetate has proved quite effective because of its antiandrogenic, antigonadotrophic, and progestational effects. (54> This agent blocks intracellular testosterone uptake as well as the intracellular metabolism of antiandrogens. As a consequence, it drastically reduces circulating testosterone and therefore reduces the paraphiliac's sexual drive. The oral dosage is usually 50 to 200 mg/ day but it is also available in an intramuscular form, requiring a dosage of 200 to 400 mg once every 1 or 2 weeks. Side-effects include liver damage, gynaecomastia (usually temporary and reversible), and reduction of sexual drive, fantasies, erections, frequency of masturbation, and sexual intercourse. This drug was first used in 1971, and a number of studies have shown it to be highly effective at reducing recidivism.(55) Ciproterone acetate is available throughout Europe and Canada, but is not available in the United States.

Pregnancy And Childbirth

Pregnancy And Childbirth

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