Effect of

In 3-day-old rats maintained under a long and a short photoperiod, respectively, and then released to darkness, there was a marked rhythm in the spontaneous c-Fos immunoreactivity in the SCN, however c-Fos was elevated for a considerably shorter

ORIGINAL LIGHT - DARK CYCLES

CYCLE 1 CYCLE 2

Figure 7. Spontaneous c-Fos immunoreactivity in the DM-SCN. Rats maintained in LD 12:12 were released into constant darkness at the time of the usual light onset at 06 h and Fos-immunoreactivity was followed in darkness for the next two cycles. Full bars denote dark periods. Adapted from Sumova et al., 1998 (35).

time as compared with the elevation in adult animals. This finding indicates a longer duration of subjective night in newborn animals (Travnickova, Sumova and Illnerova, in preparation). In 10-day-old rats, the spontaneous rhythm in Fos immunoreactivity was present in rats released to darkness from the long as well from the short pho-toperiod, however there was still no difference in duration of the elevated c-Fos immunoreactivity between these two photoperiods.

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