Clinical Studies

The sterility-associated troubles of sexual dynamics were usually accompanied by oligospermia, azoospermia, loss of erection and premature ejaculation. 60% of the cases presented a normal gonadotropic status associated with troubles of sexual dynamics and alteration of seminal fluid.

In 11 males, the levels of urinary 6-sulphatoxymelatonin were significantly lower as compared to the control group.

The high levels of 6-sulphatoxymelatonin were associated with low concentrations of FSH, LH and testosterone. Figures 5 and 6 show the urine levels of LH and FSH in patients with infertility and sexual deficiency expressed in mlU/h.

Figure 3. Effect of different melatonin doses on serum LH and FSH levels in adult GnRH-trated rats.
Figure 4. Urinary 6-sulphatoxymelatonin values in sexual dysfunction.
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