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Figure 3.11. Dependence of accumulation kinetics of single living cells (WT) upon nanoparticle concentration and incubation time. Representative plots of the number of cells with silver-enhanced gold nanoparticles versus incubation time for the cells that are incubated with 0.26, 0.52, 1.30, and 2.60 pM nanoparticles. The 400 cells in total are analyzed for each data point to ensure sufficient statistics of single-cell measurement that will represent the bulk cells at the single-cell resolution. [Reprinted from Nano Letters 2(3):175-182, with permission of American Chemical Society.]

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