Currently there is no evidence that H. pylori eradication worsen gastroesophageal reflux disease (GERD) in adults . Limited data are also available in children. However, there is a theoretical risk, even though the data are conflicting, that long-term proton pump inhibitor (PPI) treatment could increase the development of H. pylori-associated atrophic gastritis and increase the risk of gastric cancer [42, 43]. Some experts recommend testing and eradicating H. pylori if the child or adolescent is undergoing endoscopy for GERD, but not for those with clinically diagnosed GERD .
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Gastroesophageal reflux disease is the medical term for what we know as acid reflux. Acid reflux occurs when the stomach releases its liquid back into the esophagus, causing inflammation and damage to the esophageal lining. The regurgitated acid most often consists of a few compoundsbr acid, bile, and pepsin.