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Fig. 7.22 Malignant melanoma of anus with typical polypoid appearance.

{902}, fibrosarcoma, neurilemmoma and neurofibroma {571}, granular cell tumour (myoblastoma) {862}, spindle cell lipoma and aggressive angiomyxoma {503} and extraspinal ependymoma in a newborn {2074}. HIV infected persons may, in addition to the increased risk of squa-mous neoplasia, develop Kaposi sarcoma in the perianal area {113}.

Malignant lymphoma

Primary lymphomas of the anorectal region are rare in the general population, but much more common in patients with AIDS, particularly homosexual men. All are of B-cell type, the most common types being large cell immunoblastic or pleomorphic {687, 786}. Langerhans cell histiocytosis has been described in children {617, 874} and an adult {329}.

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Fig. 7.23 Malignant melanoma of anus. A Polypoid growth is frequent. B Scattered tumour cells contain melanin. C Epitheloid melanoma cells with prominent nucleoli.

Table 7.01

Anal tumours, immunoreactivity profile (exceptions occur, especially among CK and mucin)1

Table 7.01

Anal tumours, immunoreactivity profile (exceptions occur, especially among CK and mucin)1

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