Prognosis and predictive factors

The prognosis of tumours of the extrahepatic biliary tract depends primarily on the extent of disease and histological type {694, 695}. Polypoid tumours (which histologically often prove to be papillary carcinomas) have the best prognosis. Non-invasive papillary carcinomas are associated with a better prognosis than other types of invasive carcinomas. Perineural invasion and lymphatic permeation are common in the extrahepatic bile duct carcinoma and are significant prognostic factors {2150, 376}.

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