Prognosis and predictive factors

The clinical course is very unfavorable due to complications from peritonitis and malnutrition and later from progressive disease typically characterized by intestinal recurrences. The malabsorption due to underlying coeliac disease is detrimental to these patients, particularly when recovering from surgery or receiving multiagent chemotherapy {444}. Consequently, only one half of the patients is amenable to chemotherapy

Fig. 4.24 CD3 immunoexpression in a T-cell lymphoma of the small intestine.

and only a proportion of these is able to finish the complete course. The overall median survival in the largest published series is only 3 months, and 5-year survival in this and other series ranges from

8-25% {305, 424, 444}. The small group of long-term survivors usually received chemotherapy and, interestingly, none had a previous diagnosis of coeliac disease {305, 444}.

Why Gluten Free

Why Gluten Free

What Is The Gluten Free Diet And What You Need To Know Before You Try It. You may have heard the term gluten free, and you may even have a general idea as to what it means to eat a gluten free diet. Most people believe this type of diet is a curse for those who simply cannot tolerate the protein known as gluten, as they will never be able to eat any food that contains wheat, rye, barley, malts, or triticale.

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