Precursor lesions

Pancreatic neoplasms Mucinous cystic neoplasms and intra-ductal papillary mucinous neoplasms may progress to invasive cancer. In the case of mucinous cystic neoplasms, the invasive component usually resembles ductal adenocarcinoma {1781}. In the case of intraductal papillary-mucinous

Fig. 10.09 Pancreatic duct showing high-grade intraepithelial neoplasia (PanIN III).

Table 10.01

List of recommended terms with synonyms for focal hyperplastic and metaplastic duct lesions in the human exocrine pancreas.

Table 10.01

List of recommended terms with synonyms for focal hyperplastic and metaplastic duct lesions in the human exocrine pancreas.

Recommended WHO term

Previous WHO classification {947}

Other synonyms

Squamous metaplasia Incomplete squamous metaplasia

Squamous metaplasia Incomplete squamous metaplasia

Epidermoid metaplasia, multilayered metaplasia focal epithelial hyperplasia, focal atypical epithelial hyperplasia, multilayered metaplasia

PanIN-IA

Mucinous cell hypertrophy

Mucinous cell hyperplasia, mucinous ductal hyperplasia, mucoid transformation, simple hyperplasia, flat ductal hyperplasia, mucous hypertrophy, hyperplasia with pyloric gland metaplasia, ductal hyperplasia grade 1, non-papillary epithelial hypertrophy, nonpapillary ductal hyperplasia

PanIN-IB

Ductal papillary hyperplasia Adenomatoid ductal hyperplasia

Papillary ductal hyperplasia, ductal hyperplasia grade 2 Adenomatous hyperplasia, ductular cell hyperplasia

PanIN-II

Any PanIN-I lesion with moderate dysplasia as defined in the text

Was this article helpful?

0 0

Post a comment