Other variants

Carcinomas that include a spindle cell component are best termed spindle cell carcinoma or sarcomatoid carcinoma. The spindle cells are, at least focally immunoreactive for cytokeratin. The term carcinosarcoma applies to malignant tumours containing both carcinomatous and heterologous mesenchymal elements. Other rare histopathological variants of colorectal carcinoma include pleomorphic (giant cell), choriocarcino-ma, pigmented, clear cell, stem cell, and Paneth cell-rich (crypt cell carcinoma). Mixtures of histopathological types can be seen.

Carcinosarcoma

Carcinomas that include a spindle cell component are best termed sarcomatoid carcinoma or spindle cell carcinoma. The spindle cells are, at least focally, immuno-

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