The size of pancreatoblastomas varies from 1.5-20 cm. Most tumours are solitary, solid neoplasms composed of well-defined lobules of soft, fleshy tissue separated by fibrous bands. Areas of necrosis may be prominent. Uncommonly the

Fig. 10.32 Pancreatoblastoma. A CT image showing a large tumour (PB) in the head of the pancreas, with hypodense areas. B The cut surface of the neoplasm demonstrates a lobulated structure.

tumours are grossly cystic, a phenomenon reported in all cases associated with the Beckwith-Wiedeman syndrome {432}.

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