Genetic susceptibility

Carcinoids of the gallbladder and extra-hepatic bile ducts are infrequently associated with the Zollinger-Ellison, MEN I, or the carcinoid syndromes. One patient with von Hippel-Lindau syndrome and a carcinoid tumour of the extrahepatic bile ducts has been reported.

Fig. 9.21 Carcinoid tumour of common bile duct. A A band of fibrous tissue separates the tumour from normal bile duct epithelium. B Carcinoid cells with round nuclei and eosinophilic cytoplasm. C The tumour cells are immunoreactive for serotonin.

Fig. 9.21 Carcinoid tumour of common bile duct. A A band of fibrous tissue separates the tumour from normal bile duct epithelium. B Carcinoid cells with round nuclei and eosinophilic cytoplasm. C The tumour cells are immunoreactive for serotonin.

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