Pineocytoma and Pineoblastoma

Pineocytomas are histologically benign tumors that arise from primary pineal cells. They grow slowly and present with the general pattern of pineal region masses. It is reported that gross total resection is curative. Certain subsets of pineocytomas can spread through the subarachnoid space and are likely to be more biologically aggressive. Some authors advocate cranial radiation for pineocytoma. Pineoblastomas are histologically similar to primitive neuroectodermal tumors. Regions of the tumor can undergo a variety of types of differentiation. These tumors tend to disseminate through the subarachnoid space early. Gross total resection is technically difficult to achieve with these tumors, and long-term survival despite aggressive adjuvant therapy remains low.

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