Effects of Weight Loss in T2D

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In patients with T2D weight loss has been demonstrated to improve bio-markers of good health, metabolic disturbances, HbA1c and vascular complications [8]. The most striking results have been reported after massive weight loss induced by surgery. In one study [9], before surgery 49% of the patients had IGT or diabetes and after 14 years with a mean weight loss of 32.8% more than 90% maintained normal levels of plasma glucose.

In the Swedish SOS Study [10], after 10 years in the surgery group, 36% of the diabetic patients had recovered from diabetes; in contrast in the control group only 13% of patients had recovered. In the surgery group after 10 years 7% of patients and in the control group 24% of patients had developed diabetes. These data emphasize the importance of obesity contributing to the pathogenesis of T2D and provide the rationale for developing appropriate management strategies for patients with T2D.

It may be difficult to sort out benefits that can be attributed to medical nutrition therapy, diabetes education, and exercise. There are three meta-analysis studies looking at diabetes education and a variety of weight loss methods showing that nutrition interventions have the largest effect on weight loss. The weight loss again improves the metabolic control. This has been demonstrated impressively in the Diabetes Treatment Study from Northern Ireland [11] in which a successful long-term weight low was achieved with diet. The average weight loss of 9 kg after 6 months of treatment was sustained over the 6-year study. All the participating patients had recently diagnosed T2D, and diabetes was managed by diet alone in 87% of the patients at 1 year and 71% at 6 years.

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Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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