Advanced Sequencing Technologies

Worldwide, approximately US 3 billion was spent in 2005 on all aspects of genomic sequencing - the analyzer equipment and software and on sequencing reagents and enzymes. The vast majority of this sequence output was determined using CE technology with Sanger sequencing, which commensurately has been developing progressively over the past 20 years. Following the commercial release of the ''Sequencer GS20'' array pyrosequencer by the 454 Life Science Corporation (Margulies et al., 2005a, 2007),...

References

A., Doherty, E. A. S., Bogdan, F. M., Zhou, H. H. and Barron, A. E. 2001 . Impact of polymer hydrophobicity on the properties and per-hormance of DNA sequencing matrices for capillary electrophoresis. Electrophoresis 22, 737-747. Albarghouthi, M. N., Stein, T. M. and Barron, A. E. 2003 . Poly-N-hydroxyethylacrylamide as a novel adsorbed coating for protein separation by capillary electrophoresis. Elect-rophoresis 24, 1166-1175. Arora, A., Eijkel, J. C. T.,...