Evolution Of Xenobiotic Metabolism In Humans

Xenobiotics Metabolism Liver

Xenobiotics are foreign chemicals that are not a normal component of the organism that is exposed to them. This includes most drugs and many plant phytochemicals that are alien to human metabolism, but that were nonetheless a part of our ancestral diet. Humans have acquired the capability to avoid an accumulation of harmful dietary xenobiotics within cells as well as the ability to eliminate them from our bodies. To achieve this, multiple xenobiotic metabolizing enzymes with differential, but...