Treatment of VTE presenting in pregnancy

• Heparin 5-7d either monitored IV UF heparin; aim for APTT ratio 1.5-2.0

or therapeutic SC LMWH based on body wt (ffl BNF)

then monitored therapeutic SC 12-hrly UF heparin or LMWH od or bd

• Heparin requirements vary as pregnancy advances so adjust dose as necessary.

• Continue heparin until delivery; omit heparin during labour.

• Recommence heparin after delivery and start warfarin if desired.

• Continue treatment for at least 6 weeks post-partum; stop heparin once INR in therapeutic range.

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