Other causes of haemosiderosis

Dietary iron overload may also occur as a result of chronic over-ingestion of iron-containing traditional home-brewed fermented maize beverages peculiar to sub-Saharan Africa, which overwhelms physiological controls on iron absorption. Iron stores may >50g and iron is initially deposited in both hepatocytes and Kupffer cells but when cirrhosis develops, accumulates in the pancreas, heart and other organs. Over-ingestion of medicinal iron may possibly have a similar though less dramatic effect but is certainly harmful to patients with iron-loading disorders. The excessive iron absorption seen in patients with chronic liver disease is associated with accumulation in Kupffer cells rather than hepatic parenchyma. Rare congenital defects associated with iron overload have been reported.

132 This page intentionally left blank

Natural Weight Loss

Natural Weight Loss

I already know two things about you. You are an intelligent person who has a weighty problem. I know that you are intelligent because you are seeking help to solve your problem and that is always the second step to solving a problem. The first one is acknowledging that there is, in fact, a problem that needs to be solved.

Get My Free Ebook

Post a comment