1. In utero CMV -ve compatible platelet transfusions at 2-4 weekly intervals (depending on severity and history). Invasive and technically demanding. Keep platelet count >50 x 109/L (platelets 5 rapidly so frequent follow-up mandatory).

2. Maternal administration of IVIg (1g/kg) weekly from ~24 weeks onwards: check fetal platelet count ~4 weeks later and again near term; response variable—around 75% respond—transfuse platelets if non-responsive. Check cord blood at birth and treat as necessary.

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