Neoplasia

• AIDS-related Kaposi's sarcoma 20-30% of patients; multiple skin lesions; later lymph nodes, mucous membranes and visceral organs ?role of HHV8 ( >95% +ve).

• NHL up to 10%; 65% diffuse large B-cell, 30% Burkitt-like; extranodal esp. small bowel and CNS; primary effusion lymphomas; aggressive. ?role of EBV(100% +ve in 1° CNS NHL).

• Cervical carcinoma.

• Hodgkin's disease; advanced stage, extranodal sites.

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