N

t within NR or N

5 within NR or 5

PV, polycythaemia vera; SE, secondary erythrocytosis; RE, relative erythrocytosis

• Arterial oxygen saturation: pulse oximetry most convenient to detect chronic hypoxia. SaO2 <92% suggests causal relationship with absolute erythrocytosis. Sleep studies may be indicated by a history of snoring, waking unrefreshed and somnolence.

• Haematinic assays: serum ferritin: 5 or (esp. PV) and occasionally overt iron deficiency. Serum vitamin B12: levels commonly t in PV due to t transcobalamin reflecting associated granulocytosis. Folate deficiency may occur.

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