N

N/abnormal

N = normal; L = low

Defining abnormality in Glanzmann's thrombasthenia is absent aggregation to both low and high dose ADP and confirmation of membrane defect by flow cytometry with monoclonal antibodies to GPIIbllla. Similarly in BSS absent aggregation with ristocetin and confirmation by flow cytometry and monoclonal antibodies to GPIb. In the grey platelet syndrome, the platelet count is often low and the platelets pale, grey and larger than normal.

0 0

Post a comment