Investigations for Bmtpbsct

Haematology

• Serum B12 and red cell folate, ferritin.

• Blood group, antibody screen and DAT.

• Coagulation screen, PT, APTT, fibrinogen.

• BM aspirate for morphology (cytogenetics if relevant); BM trephine biopsy.

Biochemistry

Virology

302 • Hepatitis C antibody.

• HIV I and II antibody (counselling and consent required).

• Parvovirus B19 titre (allografts only).

• Toxoplasma titre (allografts only).

Immunology

• Autoantibody screen.

• HLA type—(if not known) in case HLA matched platelets are subsequently required.

• HLA and platelet antibody screen (if previously poor increments to platelet transfusions).

Bacteriology

• Baseline blood cultures (peripheral blood and Hickman line).

• Routine admission swabs: throat, central line site.

Cardiology

• Echocardiogram, to include measurement of systolic ejection fraction.

Respiratory

• Lung function tests.

Radiology

Cytogenetics

• Blood for donor/recipient polymorphisms (allografts only).

Other

• Consider semen storage.

• Dental opinion if caries/gum disease.

• Psychiatric opinion if previous history.

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