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aggression

Serum LDH

Measure of tumour aggression

Serum albumin

Hypoalbuminaemia correlates with poor prognosis

BM cytogenetics

Clear prognostic value (see beiow)

BM trephine biopsy with

Shows light chain restriction, extent of infiltration and

immunohistochemistry

haematopoietic reserve

Tests which may be useful in some patients

Creatinine clearance

With 24h protein—to assess renal damage

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