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of slow IV infusion of 70mg on day 1 followed by maintenance dose of 50mg/day (lower maintenance in moderate liver insufficiency). It may also be used for treatment of invasive aspergillosis refractory to amphotericin preparations. Caution with concomitant cyclosporin: monitor LFTs; adjust tacrolimus dose. Side effects: phlebitis, fever, headache, rash, abdominal pain, nausea, diarrhoea.

Note

As with all protocols check local policies since these may differ to those outlined in this handbook.

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