Histiocytic syndromes

Class I

Disorders of dendritic cells Langerhans cell histiocytosis

(previously known as histiocytosis X)

Class II

Disorders of macrophages Haemophagocytic syndromes

Haemophagocytic lymphohistiocytosis (HLH) Primary (genetic)

Secondary (to infection or malignant disease) Sinus histiocytosis with massive lymphadenopathy Histiocytic necrotising lymphadenitis

Class III

Malignant histiocytic disorders Malignant histiocytosis Monocytic leukaemias

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