Drugs may be divided into three risk groups

Group 1: Vesicants

Aclarubicin; amsacrine; carmustine; cisplatinum; dacarbazine; dactino-mycin; daunorubicin; docetaxel; doxorubicin; epirubicin; idarubicin; mito-mycin; mustine; paclitaxel; plicamycin; treosulfan; vinblastine; vincristine; vindesine.

Group 2: Irritants (may cause local inflammation, pain and necrosis)

Carboplatin; etoposide; liposomal daunorubicin; methotrexate; mitoxantrone (mitozantrone).

Group 3: Non-vesicants

Asparaginase; bleomycin; cladribine; cyclophosphamide; cytarabine; flu-darabine; fluorouracil; gemcitabine; ifosfamide; melphalan; pentostatin; raltitrexed; thiotepa; aldesleukin (IL-2).

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