Differential diagnosis

Exclude:

• Other causes of anaemia (haematinic deficiency, haemolysis, blood loss, renal failure).

• Other causes of neutropenia (drugs, viral infection).

• Other causes of thrombocytopenia (drugs, ITP).

• Other causes of bi-/pancytopenia (drugs, infection, aplastic anaemia).

• Other causes of monocytosis (infection, AML) or neutrophilia (infection, CML).

• Reactive causes of BM dysplasia: megaloblastic anaemia, HIV infection, alcoholism, recent cytotoxic therapy, severe intercurrent illness.

• Other causes of marrow hypoplasia in hypoplastic MDS: aplastic anaemia, PNH.

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