Clinical features

Presenting symptoms of inherited platelet dysfunction: mucocutaneous bleeding (skin, nose, gums, gut) with a positive family history (though not always found). All autosomal recessive. Clinically the bleeding symptoms are similar but may be other clinical features to distinguish the syndromes. Carriers asymptomatic. Menorrhagia may be troublesome. Symptoms may suggest the diagnosis of non-accidental injury in young children. Bleeding 372 in Glanzmann's may be severe and life threatening.

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