Childhood acute myeloid leukaemia

Acute myeloid leukaemia in children accounts for ~15% of all malignant blood disorders, with around 80-90 new cases arising in the UK each year. Unlike ALL, the disease is classified on morphological grounds using the FAB classification, as is AML in adults (ffl p150). The frequency of the different subtypes differs in children, however. M6 AML is very rare whereas M7 (megakaryocyte derived AML) is more common—especially in children with Down syndrome.

0 0

Post a comment