Causes of haemosiderinuria

Common causes Red cell enzymopathies e.g. G6PD and PK

deficiency but only during haemolytic episodes

Mycoplasma pneumonia with anti-I cold haemag-

glutinin

Sepsis

Malaria

Cold haemagglutinin disease TTP/HUS

Severe extravascular haemolysis (may cause intravascular haemolysis)

Rarer causes PNH

Prosthetic heart valves

Red cell incompatible transfusion reactions

Unstable haemoglobins

March haemoglobinuria

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