Bacterial contamination of blood products

Uncommon but potentially fatal adverse effect of blood transfusion (affects red cells and blood products e.g. platelet concentrates). Implicated organisms include Gram -ve bacteria, including Pseudomonas, Yersinia and Flavobacterium.

Features

Management—as per Immediate transfusion reaction

• Stop transfusion.

• Urgent resuscitation.

• IV broad-spectrum antibiotics if bacterial contamination suspected.

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