Subsites and Regional Lymph Node Potential

• Soft Palate: rare, since more visible than other sites typically found at early stages, 20—45% regional metastasis, 70% 5-year survival

• Base of Tongue: more aggressive tumor than oral tongue, high rate of cervical metastasis (>60%, 20% bilateral metastasis), poorer prognosis (approximately 65% 5-year survival for all stages)

• Tonsil/Lateral Pharyngeal Wall: most common site of oropharynx, may present as an exophytic mass or an ulcerative lesion, aggressive usually presents with regional neck disease (65—75%), higher instances of lymphomas and lymphoepithelomas (see below)

• Posterior Pharyngeal Wall: less common, aggressive although less metastatic potential than base of tongue

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