Benign Salivary Gland Tumors Introduction

• Risk: radiation (latency of 7-30 yrs); alcohol and smoking not associated with most salivary neoplasms (except Warthin's tumors)

• Multicellular Theory: neoplastic cells originate from their counterparts (eg, oncocytic tumors from striated duct; acinar tumors from acinar cells)

• Biocellular Theory: all neoplastic cells differentiate from basal cells found in excretory and intercalated ducts

• 80% of parotid tumors are benign; 80% of salivary neoplasms are located in the parotid

• in general, the smaller the gland the more likely malignant

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