Superior Semicircular Canal Dehiscence Mimicking Otosclerotic Hearing Loss

Rosowskia-c, Michael J. McKennaa-c aDepartment of Otology and Laryngology, Harvard Medical School, bDepartment of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, cDivision of Speech and Hearing Science Technology, Massachusetts Institute of Technology, Cambridge, Mass., USA A puzzling aspect of middle ear surgery is the presence of an air-bone gap in a small number of cases with no apparent cause. We believe that some of these cases are due to...

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Microradiography microradiography slice macroscopy slice macroscopy slice macroscopy slice macroscopy Evaluation of the temporal bone slices under the dissecting microscope revealed four temporal bones with otosclerosis (TB 2 L and R, TB 48 L and TB 110 R). Evaluation of the activity may be done even on gross inspection, active foci being fragile and hyperemic, while inactive ones being dense and pale. The case with bilateral lesions (TB 2) demonstrated a large bilobed active focus in each...

Molecular Biology of Otosclerosis

Kristiansen0 aDepartment of Otology and Laryngology, Harvard Medical School, 0Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston, Mass., USA Otosclerosis is a bone disease of the human otic capsule, which is among the most common causes of acquired hearing loss. The pathologic process is characterized 0y a wave of abnormal bone remodeling in specific sites of predilection within the endochondral layer of the temporal bone. Although the cause...

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From left to right Fisch Teflon platinum 0.4-mm piston, Teflon wire 0.6-mm piston, gold piston, wire prosthesis. entirely of stainless steel and fastened to the incus process at the top with a handle. The prefabricated, commercially available piston prostheses replaced the intraoperatively prepared wire prostheses which were made individually by the surgeon at the operating table, in order to simplify the operation, save time and ensure a standard quality. Marquet 7 , in his stapedotomy...

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They also press on cranial and spinal nerves where they exit the skull and reduce the size of the middle ear, causing conductive hearing loss. The dense bone, similar to the sclerotic mastoid bone, compresses the facial nerve, reduces the size of the middle ear, encroaches upon the middle ear ossicles, the eustachian tube, as well as the oval and round windows of the inner ear (figs. 6 and 7). The volume of the mesotympanum is decreased because the walls of the mesotympanum are thickened, and...

Stapes Surgery in Japanese Patients with Osteogenesis Imperfecta

Katsumi Doi, Hiroshi Nishimura, Yumi Ohta, Takeshi Kubo Department of Otolaryngology and Sensory Organ Surgery, Osaka University Graduate School of Medicine, Osaka, Japan Osteogenesis imperfecta (OI) is a heterogenous connective tissue disorder. The classical triad of symptoms involves a conductive and or sensorineural hearing impairment together with a tendency to spontaneous bone fractures and blue sclerae. Between 1993-2004, primary stapes surgery was performed on 14 ears of 11 OI patients...

Audiological Evaluation of Patients with Otosclerosis

Department of Otorhinolaryngology, University Hospital, Basel, Switzerland Even though the diagnosis of otosclerosis is confirmed definitively during surgery, preoperative diagnosis and determination of the indication for surgery are made based on audio-logical evaluation. Audiological tests should firmly establish a conductive component to hearing loss. The measurement of pure-tone air and bone conduction thresholds has limitations that prevent an accurate diagnosis based solely upon these...

Distortion Product Otoacoustic Emissions in Otosclerosis Intraoperative Findings

Barbaro, M. Viccaro, A. Musacchio, G. Cappelli, E. De Seta Department of Neurology and Otolaryngology, University 'La Sapienza', Rome, Italy The aim of the study was to investigate changes in middle ear dynamic characteristics caused by both otosclerosis and stapes surgery (platinotomy, prosthesis positioning, ossicular chain maneuver) and to evaluate distortion product otoacoustic emissions (DPOAEs) before and following surgery. The study included 15 patients (12...

Physical Characteristics of Various Lasers Used in Stapes Surgery

Institute of Applied Physics, University of Bern, Bern, Switzerland The invention of modern small-fenestra stapedotomy procedures using a piston-type prosthesis resulted in a remarkable hearing improvement and at the same time in a reduction of complications compared to conventionally performed stapedectomies. These procedures, however, still contain unpredictable risks such as uncontrolled stapes fracturing, luxation of the stapes or creating a floating footplate, which all can cause hearing...

Patients Lives following Stapedectomy Complications

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital, Geneva, Switzerland Nowadays, it is widely accepted that patients must be informed about the risks associated with any type of surgical procedure. Usually, the information provided consists of quoting a list of risks and their probability of occurrence based on data from the literature, and, more appropriately, the figures reflecting the surgeon's personal experience. As a rule, such data are sufficient to hold up in...

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H antigens in osteoclasts and macrophages of otosclerotic tissue strongly supports the hypothesis that MeV is involved in otosclerosis 15-17 . Detection of MeV RNA within the Otosclerotic Tissue Studies on the RNA level were undertaken to determine the presence of MeV-related sequences within the otosclerotic tissue since specificity and sensitivity of MeV antigen detection have been discussed controversially. Total RNA from fresh-frozen otosclerotic bone chips obtained during stapes surgery...

Too Much Bone The Middle Ear in Sclerosing Bone Dysplasias

Herman Hamersma, Louis Hofmeyr Florida, South Africa The middle ear changes in Sclerosteosis and Van Buchem disease are described. Reduced bone resorption occurs due to faulty activity of the sclerostin molecule, a product of the recently discovered SOST gene in chromosome 17. Syndactyly draws attention to sclero-teosis, and a conductive hearing loss develops before age six in both conditions. Acute, repeated attacks of facial palsy, similar to Bell's palsy, are usually the first symptoms in...

Dynamic Bone Studies of the Labyrinthine Capsule in Relation to Otosclerosis

Mads S0lvsten S0rensen, Thomas Frisch, Poul Bretlau Otopathological Laboratory, Department of Otolaryngology Head and Neck Surgery, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark The pathological perilabyrinthine bone remodelling of otosclerosis is associated with a genetic predisposition and triggered by mechanisms so far unknown. A proposed viral aetiology of otosclerosis originates from a similar concept of Paget's disease. However, at present, it is not clear why a virus...

Prevalence of Histologic Otosclerosis An Unbiased Temporal Bone Study in Caucasians

Declaua, M. van Spaendoncka,b, J.P. Timmermansh, L. Michaelsc, J. Liangd, J.P. Qiua,b, P. van de Heyning aDepartment of Otorhinolaryngology, Head and Neck Surgery and Communication Disorders, and bDepartment of Morphology, Laboratory of Cell Biology and Histology, University of Antwerp, Antwerp, Belgium cDepartment of Histopathology, and dInstitute of Laryngology and Otology, Royal Free and University College London Medical School, London, UK Background 'Histologic otosclerosis' refers to a...