Verrucous Carcinoma

ICD-O:8051/3

Verrucous carcinoma (VC; Ackerman's tumour) is a variant of well-differentiated SCC that was originally described by Ackerman in 1948 [5]. It is characterised by an exophytic warty growth that is slowly but locally invasive and can cause extensive local destruction if left untreated. It rarely, if ever, metastasises.

The majority of VCs (75%) occurs in the oral cavity and 15% in the larynx. In the oral cavity, the buccal mucosa and gingiva are most frequently involved, and in the larynx, the most frequent site of occurrence is the vocal cords. It rarely occurs in other locations in the head and neck, such as the nasal cavity, sinonasal tract and nasopharynx. It has been also described elsewhere in the body, i.e. the skin, anus, genitalia, urinary bladder and oesophagus [339].

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