Rhinosporidiosis

Fig. 2.3. a Sinonasal aspergilloma: densely packed branching hyphae of aspergillus forming a fungal ball. (Gomori's methenamine silver). b Sinonasal allergic mucinosis: dense aggregates of eosinophilic leukocytes distributed between pools of mucin. At the centre, one Charcot-Leyden crystal. c Allergic fungal sinusitis: scarce fungal hyphae found after diligent search in a lake of mucin (Gomori's methenamine silver)

Rhinosporidiosis is caused by the endosporulating fungus Rhinosporidium seeberi. The lesions are polypoid and occur principally in the nasal cavity [21, 161]. They are characterised by the presence of thick-walled sporangia measuring 50-350 p,m in diameter and containing numerous mucicarminophilic spores. They are associated with a heavy chronic inflammatory reaction with occasional foci of suppuration and foreign body giant cell reaction.

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