Rhinoscleroma

Rhinoscleroma is caused by Klebsiella rhinoscleroma-tis [21], a capsulated gram-negative bacillus. Large nodular tumour-like masses are found in the nasal cavity and less often in other parts of the upper respiratory tract. They contain large macrophages with abundant clear or vacuolated cytoplasm (Mikulicz cells). The causative organism may be identified by the Warthin-Starry staining method or by immu-nostaining for the Klebsiella capsular antigen. There is heavy infiltration by chronic inflammatory cells, mainly plasma cells showing numerous Russell bodies.

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