Papilloma

ICD-O:8560/0

The commonest epithelial tumours of the conjunctiva are papillomas, usually presenting as a red, papil-lomatous mass. These benign tumours histologically consist of a fibrovascular core, lined with conjuncti-val epithelium, eventually with squamous metaplasia (Figs. 10.6, 10.7). The sessile variant usually shows only

Fibrovascular Core
Fig. 10.6. Conjunctival papilloma: papillomatous mass consisting of a fibrovascular core covered with squamous metaplastic epithelium
Differentiation And Atypia Neoplasia
Fig. 10.8. Conjunctival intraepithelial neoplasia: the epithelium consists of atypical cells without orderly differentiation
Amyloidosis Skin Histopathology
Fig. 10.7. Conjunctival papilloma: detail of the squamous meta-plastic epithelium

of dysplasia, the epithelial cells show atypia (Fig. 10.8). In actinic keratosis the epithelium is thin and the stroma shows damage of elastic tissue. In the Bowenoid type mi-totic figures can be seen in the upper epithelial layers and HPV-related epithelial changes like multinucleated cells and koilocytes can be found [47, 71, 82].

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