Papillary Squamous Cell Carcinoma

ICD-O:8052/3

Papillary squamous cell carcinoma (PSCC) is an uncommon variant of SCC originally described by Crissman et al. in 1988 [75]. Its main characteristics are a papillary growth pattern and a good prognosis.

In the head and neck, PSCCs show a predilection for the oropharynx, hypopharynx, larynx, and the sinona-sal tract [75, 99, 110, 161, 343, 355]. They also occur in other parts of the body, such as the skin [15], uterine cervix [292], conjunctiva [215], and thymus [209].

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