Of Malignant Progression

Squamous cell carcinomas of the head and neck may be preceded by premalignant alterations showing epithelial changes of varying degrees. Molecular pathology has been shown to be helpful in identifying lesions at risk of further malignant progression. Chromosomal losses at loci 3p and 9p have been shown to occur in mucosal lesions that subsequently turned into cancer, but as not all of the lesions with these genetic alterations progress, other changes also play a role: additional chromosomal losses, chromosomal polysomies and p53 protein expression [204, 306]. Also, suprabasal expression of p53 protein and the presence of cells with abnormal DNA content predict malignant transformation, even in the absence of overt morphologic epithelial alterations [82, 344].

Mole Removal

Mole Removal

Moles, warts, and other unsightly irregularities of the skin can be bothersome and even embarrassing. They can be removed naturally... Removing Warts and Moles Naturally! If you have moles, warts, and other skin irregularities that you cannot cover up affecting the way you look, you can have them removed. Doctors can be extremely expensive. Learn the natural ways you can remove these irregularities in the comfort of your own home.

Get My Free Ebook


Post a comment