Neuroendocrine Carcinoma

Neuroendocrine carcinomas (NEC) of the larynx are uncommon, accounting for less than 1% of laryngeal tumours. NEC are divided into well-differentiated NEC (WD-NEC; carcinoid), moderately differentiated NEC (MD-NEC; atypical carcinoid), and poorly differentiated NEC (PD-NEC; small cell carcinoma). MD-NEC is the most common type of NEC in the larynx, followed by PD-NEC and WD-NEC [19, 92, 106].

The putative cells of origin are the Kultschitzky-like argyrophilic cells, which have been described in the human laryngeal mucosa, and are similar or identical to the Kultschitzky cells in the bronchial mucosa [285, 288]. Other possible cells of origin are the pluripotent stem cells of the surface or glandular epithelium.

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Mole Removal

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