Malignant Sinonasal Tumours

Malignant sinonasal tumours represent less than 1% of all cancers seen in humans and about 3% of all malignancies of the head and neck region [160]. Despite the low rate of malignancy arising in the sinonasal tract, a great variety of histological types of tumours may be found [216, 226]. The use of electron microscopy and more recent advances in immunohistochemistry and molecular biology have made it possible to refine the criteria for their correct recognition.

Geographical differences in the relative frequency of certain histological types of malignant sinonasal tumours may be related to variations in the exposure

Table 2.1. Malignant sinonasal tumours at the Hospital Clinic

Histological

Frequency

type of tumour

n

%

Squamous cell carcinoma

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