Malignant Lymphomas of Waldeyers ring

This section gives a brief overview of lymphomas of Waldeyer's ring. For a more detailed description, including genetic characteristics of these lymphomas see the WHO classification and the revised European-American classification of lymphoid neoplasms [74, 95]. Extranodal lymphomas of Waldeyer's ring constitute about 5-10% of all lymphomas in the USA and Europe, about 15% in Hong Kong and about 10-20% in Japan. Of all lymphomas involving Waldeyer's ring, 80% are primary to this site and the tonsillar fossa is the most common location, followed by the nasopharynx and the base of the tongue. Up to 20% of patients with tonsillar lymphoma have an associated gastrointestinal involvement. Clinical presentation is that of a localised neoplasm, sore throat, dysphagias, and in cases of nasopharyngeal involvement cranial nerve, auditory and nasal symptoms. Between 85 and 90% of all non-Hodgkin's lymphomas in Waldeyer's ring are of the B-cell phenotype, the remainder are of the T-cell type, but regional differences have been reported [146, 150]. The vast majority of Waldeyer's ring lymphomas are high-grade lymphomas, with only less than 15% being of low grade [113]. The majority of AIDS-related extranodal head and neck lymphomas are aggressive B-cell lymphomas of the Burkitt type or immunoblas-tic diffuse large B-cell lymphomas [207].

Was this article helpful?

0 0
Mole Removal

Mole Removal

Moles, warts, and other unsightly irregularities of the skin can be bothersome and even embarrassing. They can be removed naturally... Removing Warts and Moles Naturally! If you have moles, warts, and other skin irregularities that you cannot cover up affecting the way you look, you can have them removed. Doctors can be extremely expensive. Learn the natural ways you can remove these irregularities in the comfort of your own home.

Get My Free Ebook

Post a comment