Low Grade Sinonasal Adenocarcinomas

Fig. 2.14. Intestinal-type adenocarcinoma. a Papillary outgrowth of intestinal-like malignant epithelium. Destruction of sinonasal bone at the bottom. b Low-grade variant mimicking villous adenoma of the colon. c Mucinous variant mimicking mucocele respiratory tract and constitutes 5-10% of all sinonasal malignancies [43, 105, 206]. It is most common in the maxillary antrum, followed by the nasal cavity [60], although ethmoid, sphenoid and frontal sinuses may also be involved [110, 169, 255].

Other Salivary-Type High-Grade Adenocarcinomas

With the exception of adenoid cystic carcinoma, these tumours are quite rare in the sinonasal region. Although most salivary duct carcinomas (SDCs) arise from the major salivary glands, the development of this highly

Low-grade adenocarcinomas arising primarily within the s inonasal tract are an uncommon and heterogeneous group of tumours [23, 113, 139, 150]. Some of these neoplasms show apparent histological continuity with the normal surface epithelium of the sinonasal mucosa, whereas others are of salivary gland origin. All have better prognosis and different clinical presentation than their high-grade counterpart. With the exception of the well-differentiated, low-grade, adenocarcinomas of intestinal type, no correlation with occupational activities has been found in these tumours.

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