Lattice Dystrophy

Lattice dystrophy is an autosomal dominant disorder, clinically presenting in early childhood (type I) [66] or in the 2nd decade (type II) [95] with linear opacities. Histologically, eosinophilic deposits are found in the corneal stroma. They consist of amyloid and are strongly Congo red-positive [67, 112]. The disease is treated by keratoplasty.

The presence of amyloid in the corneal stroma can also be seen in chronic inflammatory conditions, these secondary amyloid deposits should not be confused with lattice dystrophy.

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