Laryngotracheobronchitis (LTB), also known as subglottic laryngitis, non-diphtheric croup, virus croup, spasmodic croup and fibrinous LTB, often occurs in children aged 1-3 years. Generally, LTB is of limited duration, caused by influenza, parainfluenza or other viruses. Prolonged infection by other pathogens may be also involved [170]. The onset of the disease is more gradual compared with acute epiglottitis. When fully developed, a croupy cough with inspiratory and expiratory stridor is present. Histologically, characteristic fibrinous laryngitis is observed with destruction of the respiratory epithelium. The mortality rate of the disease has remained low for many years [238, 353].

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