Fig. 10.30. Pseudotumour of the orbit: fibrous tissue with necrotic fat cells is infiltrated by large groups of lymphocytes. Immuno-histochemistry is necessary to rule out a malignant lymphoma and fat in the earliest stages. This will be followed by lymphocytic infiltration and end with fibrous changes. In cases of massive infiltration by lymphocytes, im-munohistochemistry is necessary to rule out malignant lymphoma (Fig. 10.30). Another disease that can mimic pseudotumours is sarcoidosis. Sarcoidosis is histologically characterised by typical granulomas, not surrounded by lymphocytes.

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