High Grade Adenocarcinomas

Adenoid Cystic Carcinoma ICD-0:8200/3

Adenoid cystic carcinoma (see Chap. 5) is the most common malignant salivary-type of tumour of the upper

Fig. 2.14. Intestinal-type adenocarcinoma. a Papillary outgrowth of intestinal-like malignant epithelium. Destruction of sinonasal bone at the bottom. b Low-grade variant mimicking villous adenoma of the colon. c Mucinous variant mimicking mucocele aggressive tumour from the seromucous glands of the upper respiratory tract may occasionally occur. We have seen one example of SDC originating in the maxillary antrum, in which the characteristic ductal pattern, with comedo-type necrosis, was only evident in the metastases to the submandibular lymph nodes. The primary tumour was initially classified as adenocarcinoma not otherwise specified (NOS) due to the absence of convincing diagnostic features [40]. Carcinoma ex pleomorphic adenoma may also occur in the sinonasal tract [110].

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